Mendelian Randomisation Study of Childhood BMI and Early Menarche

• Main Authors: Hannah S. Mumby (Author), Cathy E. Elks (Author), Shengxu Li (Author), Stephen J. Sharp (Author), Kay-Tee Khaw (Author), Robert N. Luben (Author), Nicholas J. Wareham (Author), Ruth J. F. Loos (Author), Ken K. Ong (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To infer the causal association between childhood BMI and age at menarche, we performed a mendelian randomisation analysis using twelve established "BMI-increasing" genetic variants as an instrumental variable (IV) for higher BMI. In 8,156 women of European descent from the EPIC-Norfolk co...