Metabolic Stress and Mitochondrial Dysfunction in Ataxia-Telangiectasia

• Main Authors: Goutham Narayanan Subramanian (Author), Abrey Jie Yeo (Author), Magtouf Hnaidi Gatei (Author), David John Coman (Author), Martin Francis Lavin (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ataxia-telangiectasia mutated (ATM) protein kinase is, as the name implies, mutated in the human genetic disorder ataxia-telangiectasia (A-T). This protein has its "finger in many pies", being responsible for the phosphorylation of many thousands of proteins in different signaling path...