Metabolic Stress and Mitochondrial Dysfunction in Ataxia-Telangiectasia

• Autors principals: Goutham Narayanan Subramanian (Autor), Abrey Jie Yeo (Autor), Magtouf Hnaidi Gatei (Autor), David John Coman (Autor), Martin Francis Lavin (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The ataxia-telangiectasia mutated (ATM) protein kinase is, as the name implies, mutated in the human genetic disorder ataxia-telangiectasia (A-T). This protein has its "finger in many pies", being responsible for the phosphorylation of many thousands of proteins in different signaling path...