Critical role for adenosine receptor A2a in β-cell proliferation

• Główni autorzy: Nadja Schulz (Autor), Ka-Cheuk Liu (Autor), Jérémie Charbord (Autor), Charlotte L. Mattsson (Autor), Lingjie Tao (Autor), Dominika Tworus (Autor), Olov Andersson (Autor)
• Format: Książka
• Wydane: Elsevier, 2016-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objective: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating β-cell proliferation is unknown. The objective of t...