Critical role for adenosine receptor A2a in β-cell proliferation

• Auteurs principaux: Nadja Schulz (Auteur), Ka-Cheuk Liu (Auteur), Jérémie Charbord (Auteur), Charlotte L. Mattsson (Auteur), Lingjie Tao (Auteur), Dominika Tworus (Auteur), Olov Andersson (Auteur)
• Format: Livre
• Publié: Elsevier, 2016-11-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating β-cell proliferation is unknown. The objective of t...