Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice

• Egile Nagusiak: Jialiang Zhang (Egilea), Fangyang Huang (Egilea), Li Chen (Egilea), Guoyong Li (Egilea), Wenhua Lei (Egilea), Jiahao Zhao (Egilea), Yanbiao Liao (Egilea), Yijian Li (Egilea), Changming Li (Egilea), Mao Chen (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi-Wiley, 2021-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background. After myocardial infarction, anti-inflammatory macrophages perform key homeostatic functions that facilitate cardiac recovery and remodeling. Several studies have shown that lactate may serve as a modifier that influences phenotype of macrophage. However, the therapeutic role of sodium l...