Sodium Lactate Accelerates M2 Macrophage Polarization and Improves Cardiac Function after Myocardial Infarction in Mice

• Main Authors: Jialiang Zhang (Author), Fangyang Huang (Author), Li Chen (Author), Guoyong Li (Author), Wenhua Lei (Author), Jiahao Zhao (Author), Yanbiao Liao (Author), Yijian Li (Author), Changming Li (Author), Mao Chen (Author)
• Format: Book
• Published: Hindawi-Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. After myocardial infarction, anti-inflammatory macrophages perform key homeostatic functions that facilitate cardiac recovery and remodeling. Several studies have shown that lactate may serve as a modifier that influences phenotype of macrophage. However, the therapeutic role of sodium l...