A Novel Mast Cell Stabilizer JM25-1 Rehabilitates Impaired Gut Barrier by Targeting the Corticotropin-Releasing Hormone Receptors

• Asıl Yazarlar: Yueshan Sun (Yazar), Hong Li (Yazar), Lei Liu (Yazar), Xiaoqin Bai (Yazar), Liping Wu (Yazar), Jing Shan (Yazar), Xiaobin Sun (Yazar), Qiong Wang (Yazar), Yuanbiao Guo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Mast cell (MC) plays a central role in intestinal permeability; however, few MC-targeting drugs are currently available for protection of the intestinal barrier in clinical practice. A nonfluorinated Lidocaine analog 2-diethylamino-N-2,5-dimethylphenyl acetamide (JM25-1) displays anti-allergic effec...