Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation

• मुख्य लेखकों: Taeko Kubo (लेखक), Wei-Guang Ding (लेखक), Futoshi Toyoda (लेखक), Yusuke Fujii (लेखक), Mariko Omatsu-Kanbe (लेखक), Hiroshi Matsuura (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively), at least partly via the reduction of membrane p...