Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation

• প্রধান লেখক: Taeko Kubo (লেখক), Wei-Guang Ding (লেখক), Futoshi Toyoda (লেখক), Yusuke Fujii (লেখক), Mariko Omatsu-Kanbe (লেখক), Hiroshi Matsuura (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2015-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively), at least partly via the reduction of membrane p...