Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes

• Ngā kaituhi matua: Richard Sherva (Author), Congcong Zhu (Author), Leah Wetherill (Author), Howard J. Edenberg (Author), Emma Johnson (Author), Louisa Degenhardt (Author), Arpana Agrawal (Author), Nicholas G. Martin (Author), Elliot Nelson (Author), Henry R. Kranzler (Author), Joel Gelernter (Author), Lindsay A. Farrer (Author)
• Hōputu: Pukapuka
• I whakaputaina: Open Exploration Publishing Inc., 2021-02-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Aim: Substance use disorders (SUD) result in substantial morbidity and mortality worldwide. Opioids, and to a lesser extent cocaine, contribute to a large percentage of this health burden. Despite their high heritability, few genetic risk loci have been identified for either opioid or cocaine depend...