Ensuring Sufficient Trough Plasma Concentrations for Broad-Spectrum Beta-Lactam Antibiotics in Children With Malignancies: Beware of Augmented Renal Clearance!

• Үндсэн зохиолчид: Pascal André (Зохиогч), Léonore Diezi (Зохиогч), Kim Dao (Зохиогч), Pierre Alex Crisinel (Зохиогч), Laura E. Rothuizen (Зохиогч), Haithem Chtioui (Зохиогч), Laurent Arthur Decosterd (Зохиогч), Manuel Diezi (Зохиогч), Sandra Asner (Зохиогч), Thierry Buclin (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Introduction: Broad-spectrum beta-lactams are commonly prescribed for empirical or selective treatment of bacterial infections in children with malignancies. In the immunocompromised, appropriate concentration exposure is crucial to ensure antimicrobial efficacy. Augmented renal clearance (ARC) is i...