Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer

• Asıl Yazarlar: Lijie Sima (Yazar), Zhongyuan Wang (Yazar), Ling Yu (Yazar), Youli Hou (Yazar), Dongsheng Zhao (Yazar), Bilan Luo (Yazar), Weike Liao (Yazar), Xinfu Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

ABSTRCTDysregulated HGF/c-Met pathway has been implicated in multiple human cancers and has become an attractive target for cancer intervention. Herein, we report the discovery of N-(3-fluoro-4-((2-(3-hydroxyazetidine-1-carboxamido)pyridin-4-yl)oxy)phenyl)-1-(4-fluorophenyl)-4-methyl-6-oxo-1,6-dihyd...