A Retinoid X Receptor Agonist Directed to the Large Intestine Ameliorates T-Cell-Mediated Colitis in Mice

• Κύριοι συγγραφείς: Ryohtaroh Matsumoto (Συγγραφέας), Daisuke Takahashi (Συγγραφέας), Masaki Watanabe (Συγγραφέας), Shunsuke Nakatani (Συγγραφέας), Yuta Takamura (Συγγραφέας), Yuji Kurosaki (Συγγραφέας), Hiroki Kakuta (Συγγραφέας), Koji Hase (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Retinoid X receptor (RXR) is a nuclear receptor that heterodimerizes with several nuclear receptors, integrating ligand-mediated signals across the heterodimers. Synthetic RXR agonists have been developed to cure certain inflammatory diseases, including inflammatory bowel diseases (IBDs). However, p...