The LRRC8A Mediated "Swell Activated" Chloride Conductance Is Dispensable for Vacuolar Homeostasis in Neutrophils

• मुख्य लेखकों: Philippe Behe (लेखक), Juliet R. Foote (लेखक), Adam P. Levine (लेखक), Craig D. Platt (लेखक), Janet Chou (लेखक), Fernando Benavides (लेखक), Raif S. Geha (लेखक), Anthony W. Segal (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The dialysis of human and mouse neutrophils in patch clamp experiments in the conventional whole-cell mode induces the emergence of a chloride (Cl-) current that appeared to be primarily regulated by cytoplasmic ionic strength. The characteristics of this current resembled that of the classical, and...