Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing

• প্রধান লেখক: Donavan T. Cheng (লেখক), Meera Prasad (লেখক), Yvonne Chekaluk (লেখক), Ryma Benayed (লেখক), Justyna Sadowska (লেখক), Ahmet Zehir (লেখক), Aijazuddin Syed (লেখক), Yan Elsa Wang (লেখক), Joshua Somar (লেখক), Yirong Li (লেখক), Zarina Yelskaya (লেখক), Donna Wong (লেখক), Mark E. Robson (লেখক), Kenneth Offit (লেখক), Michael F. Berger (লেখক), Khedoudja Nafa (লেখক), Marc Ladanyi (লেখক), Liying Zhang (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: BMC, 2017-05-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background The growing number of Next Generation Sequencing (NGS) tests is transforming the routine clinical diagnosis of hereditary cancers. Identifying whether a cancer is the result of an underlying disease-causing mutation in a cancer predisposition gene is not only diagnostic for a can...