Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing

Abstract Background The growing number of Next Generation Sequencing (NGS) tests is transforming the routine clinical diagnosis of hereditary cancers. Identifying whether a cancer is the result of an underlying disease-causing mutation in a cancer predisposition gene is not only diagnostic for a can...

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Main Authors: Donavan T. Cheng (Author), Meera Prasad (Author), Yvonne Chekaluk (Author), Ryma Benayed (Author), Justyna Sadowska (Author), Ahmet Zehir (Author), Aijazuddin Syed (Author), Yan Elsa Wang (Author), Joshua Somar (Author), Yirong Li (Author), Zarina Yelskaya (Author), Donna Wong (Author), Mark E. Robson (Author), Kenneth Offit (Author), Michael F. Berger (Author), Khedoudja Nafa (Author), Marc Ladanyi (Author), Liying Zhang (Author)
Format: Book
Published: BMC, 2017-05-01T00:00:00Z.
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