Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites

• Autors principals: Mari L. Lund (Autor), Kristoffer L. Egerod (Autor), Maja S. Engelstoft (Autor), Oksana Dmytriyeva (Autor), Elvar Theodorsson (Autor), Bhavik A. Patel (Autor), Thue W. Schwartz (Autor)
• Format: Llibre
• Publicat: Elsevier, 2018-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Objectives: 5-HT storing enterochromaffin (EC) cells are believed to respond to nutrient and gut microbial components, and 5-HT receptor-expressing afferent vagal neurons have been described to be the major sensors of nutrients in the GI-tract. However, the molecular mechanism through which EC cells...