LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and G_iα dependent PI-3kinase signalling

• Egile Nagusiak: Ngkelo Anta (Egilea), Meja Koremu (Egilea), Yeadon Mike (Egilea), Adcock Ian (Egilea), Kirkham Paul A (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2012-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

<p>Abstract</p> <p>COPD is a disease of innate immunity and bacterial infections are a dominant cause of exacerbations in the later stages resulting in poor health and high mortality. The pathogen-associated molecular pattern (PAMP) lipopolysaccharide (LPS) is sensed by immune cell...