Application of short tandem repeats (STRs) in the preimplantation genetic diagnosis (PGD) of α-thalassemia

• Hlavní autoři: Vu Viet Ha Vuong (Autor), Phuoc-Dung Nguyen (Autor), Nha Nguyen Thi (Autor), Phuong Le Thi (Autor), Dang Thi Minh Nguyet (Autor), Manh Ha Nguyen (Autor), Hai Anh Tran (Autor), Nhat-Min (Autor), The-Hung Bui (Autor), Thinh Huy Tran (Autor), Thanh Van Ta (Autor), Van-Khanh Tran (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2024-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Objectives: α-thalassemia is an autosomal recessive monogenic blood disorder, affecting up to 5% of the world's population. The occurrence rate of the disease in Vietnam varies up to up to 51.5%, with high rate of mutation carriers, of couples consisting of two carriers at risk of bearing a chi...