Application of short tandem repeats (STRs) in the preimplantation genetic diagnosis (PGD) of α-thalassemia

• Main Authors: Vu Viet Ha Vuong (Author), Phuoc-Dung Nguyen (Author), Nha Nguyen Thi (Author), Phuong Le Thi (Author), Dang Thi Minh Nguyet (Author), Manh Ha Nguyen (Author), Hai Anh Tran (Author), Nhat-Min (Author), The-Hung Bui (Author), Thinh Huy Tran (Author), Thanh Van Ta (Author), Van-Khanh Tran (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: α-thalassemia is an autosomal recessive monogenic blood disorder, affecting up to 5% of the world's population. The occurrence rate of the disease in Vietnam varies up to up to 51.5%, with high rate of mutation carriers, of couples consisting of two carriers at risk of bearing a chi...