A multi-task FP-GNN framework enables accurate prediction of selective PARP inhibitors

• मुख्य लेखकों: Daiqiao Ai (लेखक), Jingxing Wu (लेखक), Hanxuan Cai (लेखक), Duancheng Zhao (लेखक), Yihao Chen (लेखक), Jiajia Wei (लेखक), Jianrong Xu (लेखक), Jiquan Zhang (लेखक), Ling Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

PARP (poly ADP-ribose polymerase) family is a crucial DNA repair enzyme that responds to DNA damage, regulates apoptosis, and maintains genome stability; therefore, PARP inhibitors represent a promising therapeutic strategy for the treatment of various human diseases including COVID-19. In this stud...