Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes
Objective: Diabetic sensorimotor polyneuropathy (DSPN) affects approximately half of diabetic patients leading to significant morbidity. There is impaired neurotrophic growth factor signaling, AMP-activated protein kinase (AMPK) activity and mitochondrial function in dorsal root ganglia (DRG) of ani...
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Main Authors: | , , , , , , , , , , |
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Format: | Book |
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Elsevier,
2019-02-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |