Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes

Objective: Diabetic sensorimotor polyneuropathy (DSPN) affects approximately half of diabetic patients leading to significant morbidity. There is impaired neurotrophic growth factor signaling, AMP-activated protein kinase (AMPK) activity and mitochondrial function in dorsal root ganglia (DRG) of ani...

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Main Authors: Mohamad-Reza Aghanoori (Author), Darrell R. Smith (Author), Shiva Shariati-Ievari (Author), Andrew Ajisebutu (Author), Annee Nguyen (Author), Fiona Desmond (Author), Carlos H.A. Jesus (Author), Xiajun Zhou (Author), Nigel A. Calcutt (Author), Michel Aliani (Author), Paul Fernyhough (Author)
Format: Book
Published: Elsevier, 2019-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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