Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist S6 Stimulates Insulin Secretion From Rat Islets

• मुख्य लेखकों: Xiaohua Yang (लेखक), Min Zhang (लेखक), Zhihong Lu (लेखक), Linping Zhi (लेखक), Huan Xue (लेखक), Tao Liu (लेखक), Mengmeng Liu (लेखक), Lijuan Cui (लेखक), Zhihong Liu (लेखक), Peifeng He (लेखक), Yunfeng Liu (लेखक), Yi Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Glucagon-like peptide-1 receptor (GLP-1R) agonist-based therapeutics for type 2 diabetes mellitus have attracted worldwide attention. However, there are challenges in the development of small molecule GLP-1R agonists owing to the complexity of ligand recognition and signal induction mechanisms. Here...