Targeted Metabolomics Analysis Suggests That Tacrolimus Alters Protection against Oxidative Stress

• Autors principals: Marie Joncquel (Autor), Julie Labasque (Autor), Julie Demaret (Autor), Marie-Adélaïde Bout (Autor), Aghilès Hamroun (Autor), Benjamin Hennart (Autor), Mathieu Tronchon (Autor), Magali Defevre (Autor), Isabelle Kim (Autor), Alain Kerckhove (Autor), Laurence George (Autor), Mylène Gilleron (Autor), Anne-Frédérique Dessein (Autor), Farid Zerimech (Autor), Guillaume Grzych (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2023-07-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Tacrolimus (FK506) is an immunosuppressant that is experiencing a continuous rise in usage worldwide. The related side effects are known to be globally dose-dependent. Despite numerous studies on FK506, the mechanisms underlying FK506 toxicity are still not well understood. It is therefore essential...