Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study

• मुख्य लेखकों: Matthias Gijsen (लेखक), Erwin Dreesen (लेखक), Ruth Van Daele (लेखक), Pieter Annaert (लेखक), Yves Debaveye (लेखक), Joost Wauters (लेखक), Isabel Spriet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The impact of ceftriaxone pharmacokinetic alterations on protein binding and PK/PD target attainment still remains unclear. We evaluated pharmacokinetic/pharmacodynamic (PK/PD) target attainment of unbound ceftriaxone in critically ill patients with severe community-acquired pneumonia (CAP). Besides...