Pharmacokinetic/Pharmacodynamic Target Attainment Based on Measured versus Predicted Unbound Ceftriaxone Concentrations in Critically Ill Patients with Pneumonia: An Observational Cohort Study

• Hoofdauteurs: Matthias Gijsen (Auteur), Erwin Dreesen (Auteur), Ruth Van Daele (Auteur), Pieter Annaert (Auteur), Yves Debaveye (Auteur), Joost Wauters (Auteur), Isabel Spriet (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The impact of ceftriaxone pharmacokinetic alterations on protein binding and PK/PD target attainment still remains unclear. We evaluated pharmacokinetic/pharmacodynamic (PK/PD) target attainment of unbound ceftriaxone in critically ill patients with severe community-acquired pneumonia (CAP). Besides...