Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• Hauptverfasser: Wataru Nemoto (Verfasst von), Kotaro Yamada (Verfasst von), Osamu Nakagawasai (Verfasst von), Yoshiki Ogata (Verfasst von), Masato Chiba (Verfasst von), Ryota Yamagata (Verfasst von), Hidetomo Sakurai (Verfasst von), Koichi Tan-No (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2018-08-01T00:00:00Z.
• Schlagworte: article
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We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...