Effect of repeated oral administration of chondroitin sulfate on neuropathic pain induced by partial sciatic nerve ligation in mice

• 主要な著者: Wataru Nemoto (著者), Kotaro Yamada (著者), Osamu Nakagawasai (著者), Yoshiki Ogata (著者), Masato Chiba (著者), Ryota Yamagata (著者), Hidetomo Sakurai (著者), Koichi Tan-No (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2018-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

We examined whether chondroitin sulfate (CS), a compound used to treat osteoarthritis and joint pain, is effective against partial sciatic nerve ligation (PSNL)-induced neuropathic pain. Repeated oral administration of CS (300 mg/kg, b.i.d. for 20 days) resulted in inhibition of tactile allodynia ob...