A Single and Multiple Ascending Dose Study of Toll‐Like Receptor 7 Agonist (RO7020531) in Chinese Healthy Volunteers

• Main Authors: Andrea Luk (Author), Qiudi Jiang (Author), Katerina Glavini (Author), Miriam Triyatni (Author), Na Zhao (Author), Tomas Racek (Author), Yonghong Zhu (Author), Joseph F. Grippo (Author)
• Format: Book
• Published: Wiley, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll‐like receptor 7 (TLR7) agonists modulate broad spectrum immune activity and are evaluated in the treatment of human diseases, including cancer and chronic viral infection. RO7020531, an oral prodrug of a TLR7 agonist, is in clinical development as part of a curative regimen against chronic hepa...