A Single and Multiple Ascending Dose Study of Toll‐Like Receptor 7 Agonist (RO7020531) in Chinese Healthy Volunteers

• Autori principali: Andrea Luk (Autore), Qiudi Jiang (Autore), Katerina Glavini (Autore), Miriam Triyatni (Autore), Na Zhao (Autore), Tomas Racek (Autore), Yonghong Zhu (Autore), Joseph F. Grippo (Autore)
• Natura: Libro
• Pubblicazione: Wiley, 2020-09-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Toll‐like receptor 7 (TLR7) agonists modulate broad spectrum immune activity and are evaluated in the treatment of human diseases, including cancer and chronic viral infection. RO7020531, an oral prodrug of a TLR7 agonist, is in clinical development as part of a curative regimen against chronic hepa...