Systematic Exploration of Privileged Warheads for Covalent Kinase Drug Discovery

Kinase-targeted drug discovery for cancer therapy has advanced significantly in the last three decades. Currently, diverse kinase inhibitors or degraders have been reported, such as allosteric inhibitors, covalent inhibitors, macrocyclic inhibitors, and PROTAC degraders. Out of these, covalent kinas...

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Main Authors: Zheng Zhao (Author), Philip E. Bourne (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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