Systematic Exploration of Privileged Warheads for Covalent Kinase Drug Discovery
Kinase-targeted drug discovery for cancer therapy has advanced significantly in the last three decades. Currently, diverse kinase inhibitors or degraders have been reported, such as allosteric inhibitors, covalent inhibitors, macrocyclic inhibitors, and PROTAC degraders. Out of these, covalent kinas...
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MDPI AG,
2022-10-01T00:00:00Z.
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