Development of a UPLCâMS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study

• Váldodahkkit: Shixiao Wang (Dahkki), Yang Wang (Dahkki), Shuang Gao (Dahkki), Yuanyuan Zhang (Dahkki), Hanpei Wang (Dahkki), Longshan Zhao (Dahkki), Kaishun Bi (Dahkki), Shaojie Wang (Dahkki), Xiaohui Chen (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2017-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

A simple, rapid and sensitive method based on an ultra-performance liquid chromatographyâtandem mass spectrometry (UPLCâMS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an AC...