Development of a UPLCâMS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study

• 主要な著者: Shixiao Wang (著者), Yang Wang (著者), Shuang Gao (著者), Yuanyuan Zhang (著者), Hanpei Wang (著者), Longshan Zhao (著者), Kaishun Bi (著者), Shaojie Wang (著者), Xiaohui Chen (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2017-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

A simple, rapid and sensitive method based on an ultra-performance liquid chromatographyâtandem mass spectrometry (UPLCâMS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an AC...