ASPP2 Coordinates ERS-Mediated Autophagy and Apoptosis Through mTORC1 Pathway in Hepatocyte Injury Induced by TNF-α
Background: Though ASPP2 plays an important role in regulating cell apoptosis and autophagy in case of liver injury, there remains a lack of clarity on the molecular mechanism of ASPP2 regulating autophagy and apoptosis.Methods: A hepatocyte injury model was constructed using HL7702 cell line and TN...
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Frontiers Media S.A.,
2022-03-01T00:00:00Z.
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