Lentiviral-mediated overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus ameliorates LPS - induced cognitive impairment in mice

• Main Authors: Wei Wang (Author), Liming Zhang (Author), Xiaoying Zhang (Author), Rui Xue (Author), Lei Li (Author), Weixing Zhao (Author), Qiang Fu (Author), Weidong Mi (Author), Yun-Feng Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The 18 kDa translocator protein (TSPO) is involved in the immune/inflammatory response. However, the exact role that TSPO plays in neuroinflammation-induced cognitive impairment is still elusive. The purpose of our present study was to investigate the effects of lentiviral-mediated hippocampal overe...