Lentiviral-mediated overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus ameliorates LPS - induced cognitive impairment in mice

• Váldodahkkit: Wei Wang (Dahkki), Liming Zhang (Dahkki), Xiaoying Zhang (Dahkki), Rui Xue (Dahkki), Lei Li (Dahkki), Weixing Zhao (Dahkki), Qiang Fu (Dahkki), Weidong Mi (Dahkki), Yun-Feng Li (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The 18 kDa translocator protein (TSPO) is involved in the immune/inflammatory response. However, the exact role that TSPO plays in neuroinflammation-induced cognitive impairment is still elusive. The purpose of our present study was to investigate the effects of lentiviral-mediated hippocampal overe...