Cannabinoid Receptor 2 (CB2) Inverse Agonist SMM-189 Induces Expression of Endogenous CB2 and Protein Kinase A That Differentially Modulates the Immune Response and Suppresses Experimental Colitis

• Главные авторы: Sonia Kiran (Автор), Ahmed Rakib (Автор), Bob M. Moore (Автор), Udai P. Singh (Автор)
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• Опубликовано: MDPI AG, 2022-04-01T00:00:00Z.
• Предметы: article
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The causes of Crohn's disease (CD) and ulcerative colitis (UC), the two most common forms of inflammatory bowel disease (IBD), are multi-factorial and include dysregulation of immune cells in the intestine. Cannabinoids mediate protection against intestinal inflammation by binding to the G-prot...