Cannabinoid Receptor 2 (CB2) Inverse Agonist SMM-189 Induces Expression of Endogenous CB2 and Protein Kinase A That Differentially Modulates the Immune Response and Suppresses Experimental Colitis

• Auteurs principaux: Sonia Kiran (Auteur), Ahmed Rakib (Auteur), Bob M. Moore (Auteur), Udai P. Singh (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The causes of Crohn's disease (CD) and ulcerative colitis (UC), the two most common forms of inflammatory bowel disease (IBD), are multi-factorial and include dysregulation of immune cells in the intestine. Cannabinoids mediate protection against intestinal inflammation by binding to the G-prot...