Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia

Hypomethylating Chemotherapeutic Agents as Therapy for Myelodysplastic Syndromes and Prevention of Acute Myeloid Leukemia

Myelodysplastic Syndromes (MDSs) affect the elderly and can progress to Acute Myeloid Leukemia (AML). Epigenetic alterations including DNA methylation and chromatin modification may contribute to the initiation and progression of these malignancies. DNA hypomethylating agents such as decitabine and...

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Main Authors: Vincent G. Sorrentino (Author), Srijan Thota (Author), Edward A. Gonzalez (Author), Pranela Rameshwar (Author), Victor T. Chang (Author), Jean-Pierre Etchegaray (Author)
Format: Book
Published: MDPI AG, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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