Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist's perspective

Abstract Background [18F]fluoromisonidazole ([18F]FMISO, 1H-1-(3-[18F]fluoro-2-hydroxypropyl)-2-nitroimidazole) is a commonly used radiotracer for imaging hypoxic conditions in cells. Since hypoxia is prevalent in solid tumors, [18F]FMISO is in clinical application for decades to explore oxygen dema...

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Main Authors: Torsten Kniess (Author), Jörg Zessin (Author), Peter Mäding (Author), Manuela Kuchar (Author), Oliver Kiss (Author), Klaus Kopka (Author)
Format: Book
Published: SpringerOpen, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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