CRISPR Interference-Mediated Silencing of the <i>mmpL3</i> Gene in <i>Mycobacterium smegmatis</i> and Its Impact on Antimicrobial Susceptibility

• 主要な著者: Yonita Yuliani (著者), Azizah Fitriana Nurul Ilmi (著者), Suthidee Petsong (著者), Ajcharaporn Sawatpanich (著者), Sunisa Chirakul (著者), Tanittha Chatsuwan (著者), Tanapat Palaga (著者), Suwatchareeporn Rotcheewaphan (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: The discovery of novel therapeutic agents, especially those targeting mycobacterial membrane protein large 3 (<i>mmpL3</i>), has shown promise. In this study, the CRISPR interference-<i>Streptococcus thermophilus</i> nuclease-deactivated Cas9 (CRISPRi-dCas9<sub...