The use of genetically humanized animal models for personalized medicine approaches

• Κύριοι συγγραφείς: Annemieke Aartsma-Rus (Συγγραφέας), Maaike van Putten (Συγγραφέας), James Dowling (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: The Company of Biologists, 2020-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

For many genetic diseases, researchers are developing personalized medicine approaches. These sometimes employ custom genetic interventions such as antisense-mediated exon skipping or genome editing, aiming to restore protein function in a mutation-specific manner. Animal models can facilitate the d...