The use of genetically humanized animal models for personalized medicine approaches

• Những tác giả chính: Annemieke Aartsma-Rus (Tác giả), Maaike van Putten (Tác giả), James Dowling (Tác giả)
• Định dạng: Sách
• Được phát hành: The Company of Biologists, 2020-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

For many genetic diseases, researchers are developing personalized medicine approaches. These sometimes employ custom genetic interventions such as antisense-mediated exon skipping or genome editing, aiming to restore protein function in a mutation-specific manner. Animal models can facilitate the d...