Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy

• Main Authors: Jana Zschüntzsch (Author), Pia Vanessa Jouvenal (Author), Yaxin Zhang (Author), Florian Klinker (Author), Malte Tiburcy (Author), David Liebetanz (Author), Dörthe Malzahn (Author), Heinrich Brinkmeier (Author), Jens Schmidt (Author)
• Format: Book
• Published: Wiley, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Duchenne muscular dystrophy (DMD) is a progressive muscle‐wasting disease caused by mutations in the dystrophin gene, which leads to structural instability of the dystrophin-glycoprotein‐complex with subsequent muscle degeneration. In addition, muscle inflammation has been implic...