Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy

• Główni autorzy: Jana Zschüntzsch (Autor), Pia Vanessa Jouvenal (Autor), Yaxin Zhang (Autor), Florian Klinker (Autor), Malte Tiburcy (Autor), David Liebetanz (Autor), Dörthe Malzahn (Autor), Heinrich Brinkmeier (Autor), Jens Schmidt (Autor)
• Format: Książka
• Wydane: Wiley, 2020-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Duchenne muscular dystrophy (DMD) is a progressive muscle‐wasting disease caused by mutations in the dystrophin gene, which leads to structural instability of the dystrophin-glycoprotein‐complex with subsequent muscle degeneration. In addition, muscle inflammation has been implic...