Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application

Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application

Ethical and legal considerations have led to increased use of non-animal methods to evaluate the safety of chemicals for human use. We describe the development and qualification of a physiologically-based kinetics (PBK) model for the cosmetic UV filter ingredient, homosalate, to support its safety w...

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Main Authors: Abdulkarim Najjar (Author), Andreas Schepky (Author), Christopher-Tilman Krueger (Author), Matthew Dent (Author), Sophie Cable (Author), Hequn Li (Author), Sebastien Grégoire (Author), Laurene Roussel (Author), Audrey Noel-Voisin (Author), Nicola J. Hewitt (Author), Estefania Cardamone (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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