Use of Physiologically-Based Kinetics Modelling to Reliably Predict Internal Concentrations of the UV Filter, Homosalate, After Repeated Oral and Topical Application

• Asıl Yazarlar: Abdulkarim Najjar (Yazar), Andreas Schepky (Yazar), Christopher-Tilman Krueger (Yazar), Matthew Dent (Yazar), Sophie Cable (Yazar), Hequn Li (Yazar), Sebastien Grégoire (Yazar), Laurene Roussel (Yazar), Audrey Noel-Voisin (Yazar), Nicola J. Hewitt (Yazar), Estefania Cardamone (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Ethical and legal considerations have led to increased use of non-animal methods to evaluate the safety of chemicals for human use. We describe the development and qualification of a physiologically-based kinetics (PBK) model for the cosmetic UV filter ingredient, homosalate, to support its safety w...