The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection
Background: The significance of hepatitis B virus (HBV) in cerebrospinal fluid (CSF) is unclear. Methods: Synchronous serum and CSF samples were collected from 13 patients. HBV DNA, full-length genome, quasispecies, phylogenetic tree, compartmentalization and mutation of the reverse transcriptase (R...
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Elsevier,
2023-09-01T00:00:00Z.
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