The central nervous system is a potential reservoir and possible origin of drug resistance in hepatitis B infection

Background: The significance of hepatitis B virus (HBV) in cerebrospinal fluid (CSF) is unclear. Methods: Synchronous serum and CSF samples were collected from 13 patients. HBV DNA, full-length genome, quasispecies, phylogenetic tree, compartmentalization and mutation of the reverse transcriptase (R...

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Main Authors: Lijun Xu (Author), Minghan Zhou (Author), Xiuming Peng (Author), Yufan Xu (Author), Fan Huang (Author), Linyun Wang (Author), Xiaorong Peng (Author), Zongxing Yang (Author), Ran Tao (Author), Guanjing Lang (Author), Qing Cao (Author), Minwei Li (Author), Ying Huang (Author), Biao Zhu (Author), Yan Xu (Author)
Formato: Livro
Publicado em: Elsevier, 2023-09-01T00:00:00Z.
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