Redox-sensitive micelles for targeted intracellular delivery and combination chemotherapy of paclitaxel and all-trans-retinoid acid

• Hoofdauteurs: Lingfei Han (Auteur), Lejian Hu (Auteur), Fulei Liu (Auteur), Xin Wang (Auteur), Xiaoxian Huang (Auteur), Bowen Liu (Auteur), Feng Feng (Auteur), Wenyuan Liu (Auteur), Wei Qu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The application of paclitaxel (PTX) in clinic has been restricted due to its poor solubility. Several traditional nano-medicines have been developed to improve this defect, while they are still lack of tumor targeting ability and rapid drug release. In this work, an amphiphilic polymeric micelle of...