Redox-sensitive micelles for targeted intracellular delivery and combination chemotherapy of paclitaxel and all-trans-retinoid acid

• Main Authors: Lingfei Han (Author), Lejian Hu (Author), Fulei Liu (Author), Xin Wang (Author), Xiaoxian Huang (Author), Bowen Liu (Author), Feng Feng (Author), Wenyuan Liu (Author), Wei Qu (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The application of paclitaxel (PTX) in clinic has been restricted due to its poor solubility. Several traditional nano-medicines have been developed to improve this defect, while they are still lack of tumor targeting ability and rapid drug release. In this work, an amphiphilic polymeric micelle of...